What is plasma enriched in growth factors PRGF?
Platelet-enriched plasma is a technique that has been widely described in other medical specialties such as traumatology, ophthalmology, etc. Now this technique is evolving to serve assisted reproduction.
This new technology is based on the use of the patient’s plasma enriched in growth factors. It is autologous plasma, that is, the patient’s own plasma, and through its preparation the growth factors are concentrated and then used in the woman’s endometrium.
The advantages of PRGF
A simple and easy technique for all patients.
- Safety: it reaches the clinical care clinic after many studies that demonstrate its benefits.
- Versatility: the applications are many, and we describe them below.
- Simplicity: only one blood collection is required and the amount obtained can be used for several doses, even for a whole year.
- Painless: once the blood is obtained, the plasma is prepared and then introduced into the endometrium (on the indicated days) with a cannula as in artificial inseminations. It does not hurt or bother, is performed in the office and lasts only a few minutes.
- Biocompatibility: there are no allergic reactions, rejection or side effects, since it is the patient’s own plasma. The patient’s own plasma.
PRGF applications in assisted reproduction
- Endometriums that do not grow. The thickness of the endometrium for embryo implantation is critical. It does not always depend on the medication, so it is applicable for those cases in which the thickness does not reach adequate values.
- Implantation failure. When at least one failed transfer has occurred, implantation rates improve after this technique.
- Repeated miscarriages. Data are supporting the application of PRGF to improve endometrial vascularization, which could be a cause of early miscarriages.
How is the PRGF technique performed?
The first step is to make an appointment to draw blood (a normal blood draw); that same day the sample is treated, the plasma is enriched in growth factors by processing and centrifugation. This sample can be stored frozen for later use.
During the week prior to the embryo transfer, 3 inoculations will be performed 2-3 days apart. A transfer cannula is used as those used in embryo transfer through the cervix and does not require sedation or any type of anesthesia.
It is a completely painless process that is performed almost routinely, with highly successful results.
At the ERGO Clinic we always put the latest technology at the service of our patients. Ask us about your case and we will guide you on what you need to achieve your dream.